RERconverge on GitHub
RERconverge is a set of software written in R that estimates the correlation between relative evolutionary rates of genes and the evolution of a convergent binary or continuous trait across a phylogeny.
ERC measures correlated rates across a phylogeny, allowing for extraction of genes with similar evolutionary histories. High ERC values are typically observed between genes participating in a common pathway or that otherwise share functionality.
Datasets and Repositories Accompanying Papers
2019 Raza et al. PLOS Genetics [ https://datadryad.org/stash/dataset/doi:10.5061/dryad.fp45s43 ]
Data from: Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila
2018 Meyer et al. Science. [ https://github.com/nclark-lab/MarineFxLoss ]
This repository contains scripts associated with a genome-wide screen for convergent loss of gene function in marine mammals.
2012 Clark, Alani, Aquadro. Genome Research
ERC Yeast Dataset 2012
[zip file yeastERC ]