Software

RERconverge on GitHub

RERconverge is a set of software written in R that estimates the correlation between relative evolutionary rates of genes and the evolution of a convergent binary or continuous trait across a phylogeny.

 

RERconverge Walk-Throughs

Full step-by-step instructions (pdf or html) on how to identify genetic elements correlated with the convergent evolution of your trait of interest.

 

ERC Analysis Webserver

ERC measures correlated rates across a phylogeny, allowing for extraction of genes with similar evolutionary histories. High ERC values are typically observed between genes participating in a common pathway or that otherwise share functionality.

 


Datasets and Repositories Accompanying Papers

2019 Raza et al. PLOS Genetics [ https://datadryad.org/stash/dataset/doi:10.5061/dryad.fp45s43 ]
Data from: Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila

 

2018 Meyer et al. Science. [ https://github.com/nclark-lab/MarineFxLoss ]
This repository contains scripts associated with a genome-wide screen for convergent loss of gene function in marine mammals.

 

2012 Clark, Alani, Aquadro. Genome Research
ERC Yeast Dataset 2012
[zip file yeastERC ]

Our Collaborators